Efficient determination of solubility curves

Acquire solubility data at an early stage

Solubility is the foundation piece of information on which any solid-state screening and solid form process is based on. The Crystal16 has been designed from the ground up to provide you with accurate polythermal solubility data faster and easier than traditional methods. By using 16 individual reactors in 4 parallel reactor blocks, the device can quickly generate solvent/antisolvent libraries and give you the solubility and MSZW curves required for your research project.

Using a Crystal16 with 16 vials holding 4 different concentrations of a drug substance in 4 different solvents and applying 2 temperature cycles with a heating rate of 0.5 °C/min and a cooling rate of 1 °C/min, 4 solubility curves can be measured in duplicate in half a day.

Discover why several pharmaceutical companies have already chosen the Crystal16 as their standard tool to determine solubility of their drug compounds.