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Process development

Design and control your crystallization process

Take control of the crystallizaiton process development

In the manufacturing of solid dose formulations, crystallization is a commonly used process. A well designed and controlled crystallization process can be used to substantially improve the economical and biological performance of a drug molecule through exerting control over particle size distribution and morphology, polymorphic form, and purity. Therefore, in order to maximize the benefits of a crystallization, a thorough understanding is required which can be done though modeling, design of experiment stress testing and the use of process analytical technologies (PAT). Using the Crystalline instrument, it is possible to generate information about the solid form, as well particle size and morphology. By making use of the integrated particle viewer and Raman spectroscopy, one may accelerate the development process of the drug development at an earlier stage and using less material.