Content overview
Polymers are used extensively across a wide range of industries, including pharmaceuticals, paint and coatings, packaging, cosmetics, and medical devices, due to their highly tunable structures and properties. However, broad molecular weight distributions, slow dissolution and precipitation kinetics, and strong temperature-dependent phase behavior all contribute to experimental variability of this category of materials. This sensitivity underscores the need for well-controlled, high-quality experimental methods when studying polymer solubility.
This application note presents a way to develop a standardized and reproducible workflow for measuring polymer–solvent solubility across systems exhibiting LCST and UCST behavior, using the Crystal16 instrument.
Reference
We acknowledge the following published study, and we are deeply thankful to the authors for their valuable contributions polymer research utilizing the Crystal16 instrument.
Amrihesari, M., Murry, A. & Brettmann, B. Towards standardized polymer solubility measurements using a parallel crystallizer. Polymer 278, 125983 (2023).
