Highly automated workflows for rapid development of chemical processes

  • Reaction
  • 3 June 2025, Online

About

As a program transitions into late-stage development, process chemistry development requires thorough understanding of the reaction conditions, workup, and isolation. Building knowledge in each facet of the process ensures a robust execution when the process is scaled, which is further strengthened by the ability to collect a high volume of data in a short amount of time with little material. The rapid development of a robust chemical process and the use of highly automated workflows and tools to define process parameters, with additional evaluation of the workup and isolation. Data collected using these workflows allowed for the design of a reproducible process from vial to hundred kilogram scale.  

Guest speaker

Bilal Hoblos, PhD

Senior Scientist at BMS

Dr. Bilal Hoblos is a Senior Scientist within the Chemical Process Development Department at Bristol Myers Squibb. Prior to starting in August 2021, he completed his PhD at Temple University in Prof. Sarah Wengryniuk’s group where he focused on the total synthesis of natural products using novel hypervalent iodine-mediated ring expansion methodology. Since being at BMS, he has gained experience in early and commercial-stages of drug development of small molecules and biomolecules with the primary goals of delivering robust processes and high quality intermediates or API’s.  

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If you are curious to explore more case studies on chemical process R&D and the ReactALL, then check out these application notes in our Library.

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