About the workshop
We are delighted to invite you to our upcoming in-person workshop hosted by Technobis Crystallization Systems in partnership with Rowan University.
Date: 4th of October 2023
Place: Rowan University, New Jersey, USA
Topic: Crystallization: Nucleation, Applications and Process Optimization
The workshop will bring together researchers interested in crystallization, nucleation, and process development looking to solve day-to-day crystallization challenges and optimize their best practices.
Participants have a chance to learn the latest trends in the field from the keynote speakers from both industry and academia while networking with crystallization industry colleagues.
Check out the agenda, speakers and register below.
Agenda:
9:00 - 9:30 — Registration and coffee
9:30 - 9:45 — Opening remarks
09:45 - 11:00 — Training session Crystal16: nucleation rate from induction time | Jyoti Yadav, M.Sc. | Technobis Crystallization Systems
11:00 - 11:15 — Coffee break
11:15 - 12:15 — Presentation Material-sparing methods for early crystallization development using the Technobis Crystalline | Dr. Gerard Capellades | Rowan University and Dr. Alpana Thorat | Pfizer
12:15 - 13:00 — Presentation Effects of molecular rigidity and purity on crystallization pathways and kinetics | Dr. Lotfi Derdour | GSK
13:00 - 14:15 — Lunch
14:15 - 15:00 — Presentation Impact of low-level hydrogen-bonding impurities on nucleation rates | Dr. Carlos Pons Siepermann | Merck
15:00 - 15:45 — Presentation Strategic isolation of API synthetic intermediates using Crystal16 and Crystalline | Dr. Martin Glavinovic | Eurofins Alphora
15:45 - 16:00 — Coffee break
16:00 - 17:15 — Training session Crystalline: crystallization development with real time PSD measurements | Dr. Thomas Kendall | Technobis Crystallization Systems
17:15 - 17:30 — Closing remarks
Speakers
Gerard Capellades, Ph.D.
Assistant Professor | Rowan University
Dr. Gerard Capellades' research group works on understanding the role of solvents and impurities on small-molecule crystallization kinetics, on the development of novel diagnostics and process design strategies for drug purification, the application of high-throughput experimentation and digital twins for crystallization process design, and on the design of sustainable solutions for water desalination using crystallization.
Alpana Thorat, Ph.D.
Senior Scientist-Crystallization Process Development | Pfizer
Dr. Alpana Thorat is currently working as a Senior Scientist in Crystallization Technologies Laboratory (CTL) group of Pfizer Chemical R&D in Groton CT. She has PhD in Chemical Engineering from Indian Institute of Technology Gandhinagar (India). After completing PhD, she moved to USA for postdoctoral training. She has worked on Amorphous Solid Dispersions for Food Products (Purdue University-Prof Lynne Taylor Group), Lyophilization of Protein Based Formulations (University of Minnesota - Prof Raj Suryanarayanan Group), and Continuous Crystallization in Plug Flow Reactor and High Concentration Protein Formulation Spray Drying (MIT - Prof Allan Myerson Group). She also worked as Senior Research Chemist (2008-2009) at Sai Life Sciences India Pvt Ltd. Dr. Thorat’s current industrial work focuses on batch and continuous crystallization, building workflows for automating crystallization development. She is also active member of Diversity Equity and Inclusion team of CRD Groton at Pfizer.
Lotfi Derdour, Ph.D.
Associate Director | GSK
Lotfi Derdour completed his Bachelor's degree in Chemical Engineering as top student in 1993 from University of Science and Technology, Oran, Algeria. He obtained his master's in Industrial Chemistry in 1994 from University Claude Bernard, Lyon, France. Lotfi developped semi-empirical models for convective drying during his doctoal and obtained his PhD from University Claude Bernard, Lyon, France, in 1999. He then held a postdoctoral position with CNRS, France, where he conducted studies on the application of in situ infrared spectroscopy to monitor and control crystallization processes from impure stream. Lotfi has been working in API process development with a focus on particle formation and isolation for 20+ years. Lotfi published 18 original research articles mainly in crystallization and drying and authored 6 patents in crystallization and solid state.
Carlos Pons Siepermann, Ph.D.
Associate Principal Scientist | Merck
Dr. Carlos Pons Siepermann was born in Caracas, Venezuela. He came to the USA to study Chemical Engineering at the University of Michigan. He obtained his bachelor’s degree in 2013. He then completed his masters and Ph.D in Chemical Engineering Practice at MIT in 2018, working for Professor Allan Myerson. His thesis was focused on evaluating the impact of hydrogen-bonding additives on crystallization processes, with a focus on impurity rejection and primary nucleation. After his work in academia, he began his journey in industry as a pharmaceutical process development engineer in Bristol Myers Squibb. In 2021 he transitioned into his current position as an Associate Principal Scientist for the Crystallization Laboratories (X-Labs) of Merck’s Chemical Engineering Research and Development team.
Martin Glavinovic, Ph.D.
Senior Research Scientist Solid State R&D | Eurofins Alphora
Born and raised in Montreal, Martin Glavinović studied Chemistry at McGill University, receiving both a B. Sc. and M. Sc. For his M. Sc., he studied under Professors Tomislav Friščić and Jean-Philip Lumb. His research focussed on mechanochemical redox reactions, reacting metals and non-innocent ligands in the solid-state by mechanical grinding. For his Ph. D., he studied under Professor George Shimizu at the University of Calgary. His Ph. D. thesis titled “Porous metal-phosphonate materials with orthogonalized linkers” focussed on designing new organic linkers to self-assemble resilient metal-organic frameworks for gas separations. Upon successfully defending his thesis, Martin was recently hired by Eurofins Alphora as a senior scientist in their solid-state research and development division. There, he works in tandem with Alphora’s synthetic organic team, developing crystallization protocols for APIs and their synthetic intermediates.
Join us!
Participation at this workshop is free of charge.
Please note this is an in-person workshop.
Registration is mandatory and can be done via the link below.