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October 2018

Is Your Crystallization Development Workflow Ready for 2019?

October 30th, 2018

Since 2004, Crystallization Systems has helped scientists around the world with process analytical technology (PAT) based small scale equipment by providing solutions in crystallization development....

Modeling Approaches to Increase the Efficiency of Clear-Point-Based Solubility Characterization

October 16th, 2018

The clear point method for solubility characterization is well-suited to early-stage solvent screening because it does not require sampling or sample analysis. Efficient application of this...

Particle Size Control During Recrystallization and Scale-up

October 16th, 2018

A variety of approaches exist for particle size control of active pharmaceutical ingredients during process development and scale up for the production of solid oral dose medicines, including reactive...

Nucleation and Growth Kinetics for Combined Cooling and Antisolvent Crystallizationin an MSMPR System: Estimating Solvent Dependency

October 16th, 2018

Nucleation is one of the key phenomena in crystallization as it initiates crystal formation in a running crystallization process and it controls particle attributions, such as polymorphism and size...

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